Health Condition 1: D331- Benign neoplasm of brain, infratentorial
Conditions
Interventions
Intervention1: Dexmeditomidine: Dexmeditomidine infusion started in test group 30 min before induction at the rate of 1mcg/kg/hr for 10min and then 0.4mcg/kg/hr till skin closure
Control Intervention1
Sponsors
Rajendra Institute Of Medical Science
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade- 1&2 surgery duration 4-5 hr elective surgeries infratentorial tumor surgery GCS not less than 14-15
Exclusion criteria
Exclusion criteria: hypertensive on other alpha 2 agonist severe intracranial hypertension preoperative heart rate less than 45 2&3 degree AV block patient on anti arryhthmic drug and beta blocker anticipated difficult intubation hypersenstivity to test drug pregnancy morbid obesity patient with chronic lung, renal and hepatic disease post head injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To observe the effect of dexmedetomidine on Heart rate, Systolic blood pressure, Diastolic blood pressure, Mean arterial pressure during intraoperative period.Timepoint: baseline before induction every 5 min after induction end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| intraoperative fentanyl requirementTimepoint: Intraoperative period from induction of anesthesia till end of surgery;Minimum alveolar concentration [MAC] of isoflurane to maintain optimum hemodynamics required for the surgeryTimepoint: intraoperative period from induction of anesthesia till end of surgery | — |
Countries
India
Contacts
Public ContactDr Priyanka Shrivastava
Rajendra Institute Of Medical Science
Outcome results
None listed