The assessment of study is by comparing vitamin b12 and benzydamine hydrochloride spray in radiation mucositis patients

Comparative Assessment of Efficacy of Vitamin B12 spray versus Benzydamine Hydrochloride spray in Prevention and Management of Radiation Mucositis-A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076607

Enrollment

Registered

2024-11-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Vitamin B12 Spray: will be given orally which needs to be sprayed on the mucosal surfaces for 8 weeks Control Intervention1: Benzydamine Hydrochloride: will be given orally which needs

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS WILLING TO PARTICIPATE IN THE STUDY PATIENTS WITH HEAD AND NECK CANCER WHO ARE PLANNED FOR RADIOTHERAPY

Exclusion criteria

Exclusion criteria: Patients who are not willing for the study Patients who are on ryles tube Patients who are on respiratory support

Design outcomes

Primary

Measure	Time frame
Pain score using visual analog scale every week for 8 weeks Erythema using WHO assessment scale every week for 8 weeksTimepoint: Pain score using visual analog scale every week for 8 weeks Erythema using WHO assessment scale every week for 8 weeks	—

Secondary

Measure	Time frame
TO KNOW THE EFFICACY OF VITAMIN B12 SPRAYTimepoint: GIVEN FOR 8 WEEKS	—

Countries

India

Contacts

Public ContactRakesh Kumar Manne

Narayana Dental College and Hospital

rmannae@reddiffmail.com9704014747

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026