Post-Operative Amino acid supplementation for the patients under went head and neck cancer surgeries.

Post-Operative Intravenous Amino acid supplementation in major head and neck cancer flap surgeries.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076602

Enrollment

Registered

2024-11-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C760- Malignant neoplasm of head, face and neck

Interventions

Intervention1: 10% Amino acid infusion: 10% Amino acid infusion – 500 ml bottle (50 cc/h over 10 h) at POD 1 to 7 Control Intervention1: NA: NA

Eligibility

Inclusion criteria

Inclusion criteria: All head and neck cancer patients, Squamous cell carcinoma – early and advanced T 2/T3/T4a , cancers {mandible, Floor of the mouth, tongue, maxilla, buccal mucosa, laryngeal, hypopharyngeal } with resection involving a flap- pedicled/ free flap and needing adjuvant treatment.

Exclusion criteria

Exclusion criteria: 1. Patients on Immunosuppression/steroid 2. Not willing for participation 3. Patients with poor performance status 4. Patients with recurrent cancer 5. Patients Post RT SCC

Design outcomes

Primary

Measure	Time frame
i. early drain removal ii. earlier discharge iii.earlier starting of Radiotherapy in post operative period supplementation leads to earlier starting of Radiotherapy in post operative periodTimepoint: at discharge	—

Secondary

Measure	Time frame
Orocutaneous fistula rate, flap resuturing rate/ debridement rate, flap necrosis, reflap surgeryTimepoint: at discharge	—

Countries

India

Contacts

Public ContactDr Hemanth Kumar Singh

AIIMS Mangalagiri

Hemant.surgicaloncology@aiimsmangalagiri.edu.in8903306321

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026