A clinical trial to study the retention and marginal integrity of two pit and fissure sealants viz. moisture-tolerant and moisture-intolerant pit and fissure sealants, at 3 and 6 months, in permanent molars with deep pits and fissures susceptible to dental caries, in children aged 6 to 12 years.

Comparative evaluation of retention of hydrophilic and hydrophobic pit and fissure sealants in permanent molars at 3 and 6 months - an in-vivo study. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076524

Enrollment

156

Registered

2024-11-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K08- Other disorders of teeth and supporting structures

Interventions

Intervention1: Hydrophilic pit and fissure sealant: Hydrophilic pit and fissure sealant is a moisture-resistant resin sealant and does not have bisphenol A-glycidyl methacrylate (bis-GMA). Retention,

Eligibility

Inclusion criteria

Inclusion criteria: 1. 6 Ã¢â?¬â?? 12 year old healthy children. 2. All fully erupted non carious permanent molars. 3. Contralateral molars. 4. No history of any fluoride application from last 6 months or sealant application on molars. 5. Children with high risk of caries. 6. Presence of bilateral maxillary and mandibular molars on both sides.

Exclusion criteria

Exclusion criteria: 1. Children with hypoplastic teeth. 2. Uncooperative children.

Design outcomes

Primary

Measure	Time frame
Retention rates and marginal integrity of hydrophilic and hydrophobic pit and fissure sealants.Timepoint: 3 and 6 months	—

Secondary

Measure	Time frame
Caries incidence after application of pit and fissure sealants.Timepoint: 3 and 6 months.	—

Countries

India

Contacts

Public ContactDr Anand C Poal

Maharishi Markandeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana.

hod.pedodontics@mmumullana.org8197793383

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026