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A study comparing Mephentermine vs Phenylephrine in patient undergoing LSCS under spinal anesthesia

A Comparative Study Of Effects Of Mephentermine versus Effects Of Phenylepherine In Patient Undergoing Lscs Under Spinal Anesthesia - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076508
Enrollment
100
Registered
2024-11-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: (Mephentermine) bolus dose 6 mg: Participants will receive Inj. Mephentermine iv bolus dose 6 mg as the primary vasopressor during spinal anesthesia if the MAP falls below 65 mmHg or Sy

Sponsors

Dr Saksham Garg
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II Patients who gave written informed consent

Exclusion criteria

Exclusion criteria: ASA grade III or greater Base line heart rate less than 60 bpm Base line blood pressure less than 100 by 60 mmhg Multiple Gestation Participants with a history of significant cardiovascular diseases, such as coronary artery disease or heart failure, will be excluded Women with pre-existing renal dysfunction or renal diseases will be excluded due to potential complications related to vasopressor use Participants with pre-existing diabetes mellitus will be excluded, as diabetes can influence vascular responsiveness Women with known allergies or sensitivities to Mephentermine or Phenylephrine will be excluded

Design outcomes

Primary

MeasureTime frame
Blood PressureTimepoint: 1, 2, 3, and 5 mins after subarachnoid block for the first 5 mins minutes and every 5 min thereafter till the delivery of the baby

Secondary

MeasureTime frame
Heart RateTimepoint: 1, 2, 3, and 5 mins after subarachnoid block for the first 5 mins minutes and every 5 min thereafter till the delivery of the baby

Countries

India

Contacts

Public ContactDr Arushi Saxena

Varun Arjun Medical College and Rohilkhand Hospital

dratulagarwal88@gmail.com9837034245

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026