None listed
Conditions
Interventions
Intervention1: Arm 2 â??600 IU/d enhanced dried mushroom powder: Cookies and cutlets incorporated with enhanced dried mushroom powder (600 IU)
Frequency is daily
Total Duration - 12 weeks (3 months)
Sponsors
Dr. Pratibha Dwarkanath
Eligibility
Inclusion criteria
Inclusion criteria: 1. Young adults of both sexes aged 18 to 30 years who are overweight or obese with BMI more than 24.9 kg/m2 will be included in the study. 2. Vitamin D deficiency on screening with serum vitamin D levels less than 20 ng/mL or 50 nmol/L. 3. Participants willing to consume vitamin D2 enhanced mushroom powder in the form of home based snacks daily for 3 months. 4. Participants willing to undergo blood collection of 5 mL venous blood at three time points for evaluation of vitamin D status, total vitamin D, vitamin D2, vitamin D3, PTH and OGTT profile including fasting, 1 hour, 2 hour and 3 hour blood samples at baseline, 3 months after intervention and 3.5 months. Urine collection for calcium and creatinine ratio will be done at 1.5 months.
Exclusion criteria
Exclusion criteria: 1)Participants with mushroom food allergy, severe anemia. 2)Participants who are underweight (BMI less than 18.5 kg/m2) and normal (BMI: 18.5 â?? 24.9 kg/m2) will be excluded and consuming vitamin D tablets or tablets which may influence vitamin D absorption. 3) Abnormal biochemical parameters of liver and kidney function tests. 4) Discontinue the supplementation regime before the completion of the study/ move out of the study site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome name: Change in total vitamin D serum level and insulin resistance, time point: 3 months (12 weeks).Timepoint: 3 months (12 weeks). | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessing the delta change in serum vitamin D2 and vitamin D3 forms and PTH levels.Timepoint: 3 months (12 weeks) | — |
Countries
India
Contacts
Public ContactDr Pratibha Dwarkanath
St. Johnâ??s Research Institute
Outcome results
None listed