Health Condition 1: I959- Hypotension, unspecified Health Condition 2: A419- Sepsis, unspecified organism
Conditions
Interventions
Intervention1: ABCDEF BUNDLE: Participants in this group will be applied ABCDEF bundle, i.e. 6 components viz
Assess, prevent and manage pain,
Both spontaneous awakening and breathing trials,
Choic
Sponsors
Postgraduate institute of medical education and research
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients =18 years of age presented with sepsis ( SOFA score=2 for patient with no pre-existing organ dysfunction and acute change in SOFA score by =2 in a patient with pre-existing organ dysfunction) will be included in the study trial.
Exclusion criteria
Exclusion criteria: Patients expected to have hospital stay less than 2 days of duration. Patients who are unable to understand a common language due to visual, auditory or linguistic problems (unable to speak English, Hindi or Punjabi). Patients who come under surgical unit. Patients who come under trauma unit. Patient who is pregnant. Patient who has any evidence of meningitis or meningoencephalitis. Patient who has any evidence of central nervous system disorder that is considered not to be caused by sepsis based on clinical examination e.g. Stroke, severe head trauma, brain tumour, cerebrovascular dementia and Alzheimer’s disease). Patient denying for informed consent. Patient who are COVID-19 RT-PCR positive. Patients with drug intoxication. Patients having withdrawal syndromes. Patients diagnosed with envenomation. Patients who are undergoing end of life care.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of deliriumTimepoint: 14 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of delirium. Length of stay in mechanical ventilation. Length of stay in ICU. Dose of antipsychotics. Mortality.Timepoint: 14 days | — |
Countries
India
Contacts
Public ContactDr Saurabh C Sharda
Postgraduate institute of medical education and research
Outcome results
None listed