Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
All India Institute of Medical Sciences Bathnida
Eligibility
Inclusion criteria
Inclusion criteria: Patients having moderate to severe plaque psoriasis with psoriais area and severity index more than 10 Patients not taking any systemic treatment since last 1month Patients who are willing to sign the written consent form before participating in the study
Exclusion criteria
Exclusion criteria: Patients having connective tissue disorders Patients with diabetes mellitus or peripheral vascular disease or coronary disease or cerebrovascular disease Patients with active visible trauma or cosmetic operations or those with a history of professional finger trauma Pregnant and lactating females Patients with contraindications to methotrexate therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the nailfold capillaroscopic findings in the patients of psoriasis at baseline and psoriasis area severity index 75 after methotrexate therapyTimepoint: At baseline and at PASI75 OR 16th week whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate nailfold capillaroscopic findings with the biochemical marker of endothelial functionTimepoint: At baseline only | — |
Countries
India
Contacts
Public ContactDr Shivani Bansal
All India Institute of Medical Sciences Bathinda
Outcome results
None listed