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Dexmedetomidine versus low molecular weight dextran will be used as adjuvant to Ropivacaine in ultrasound guided erector spinae plane block for postoperative analgesia in patients undergoing Total Abdominal Hysterectomy.

Dexmedetomidine versus low molecular weight dextran as adjuvant to Ropivacaine in ultrasound guided erector spinae plane block for postoperative analgesia in Total Abdominal Hysterectomy - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076412
Enrollment
96
Registered
2024-11-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D259- Leiomyoma of uterus, unspecified

Interventions

Intervention1: Erector Spinae Plane block: Group A (Control group): 40ml 0.25% Ropivacaine(20ml on each side) in Normal Saline (in 1:1 ratio) Control Intervention1: ESPB with Ropivacaine: Group A (Con

Sponsors

Swami Rama Himalayan University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ? All Patients giving written informed consent Females undergoing elective Abdominal Hysterectomy surgeries. American Society Of Anaesthesiology(ASA) physical status Grade I, II Incision- Pfannenstiel

Exclusion criteria

Exclusion criteria: Patient’s refusal to participate in study Cognitive impairment or active psychiatric condition Infection at local site Bleeding disorders Contraindications to any of the drugs used in the study(allergy) Lactation Drug abuse Severe liver and kidney disease ASA=3 Midline incision Dyscholestrolemia Severe cardiovascular/Respiratory risk Coagulation disorders Allergy to local anaesthetic

Design outcomes

Primary

MeasureTime frame
total amount of opioid consumption in first 24 hoursTimepoint: 24 hours

Secondary

MeasureTime frame
1. Time of first rescue analgesic request( time from PACU shifting to first requested rescue analgesic)Timepoint: 24 hours;Total amount of prescribed analgesic in PACUTimepoint: 24 hours;Any opioid related side effects like respiratory depression, pruritis within the first 24 hours.Timepoint: 24 hours

Countries

India

Contacts

Public ContactHarish Koshyari

Himalayan Institute of medical Sciences

harish834@gmail.com8979678923

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026