Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems Health Condition 3: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems
Conditions
Interventions
Intervention1: dexmedetomidine infusion20 minutes prior: Starting infusion of dexmedetomidine 0.75mcg/kg over 10 minutes. 20 minutes before induction of general anaesthesia
Control Intervention1: dexm
Sponsors
Institute Of Medical Sciences Banaras Hindi University
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patients posted for elective surgey under general anaesthesia and undergoing endotracheal intubation. 2)Elective surgery lasting less than 2 hours. 3)Patient in which laryngoscopy time asts less than 30 seconds. 4)ASA grade 1&2 physical status.
Exclusion criteria
Exclusion criteria: 1)Patient refusal 2)Patient taking cardiovascular drrugs. 3)Patient in which we anticipate difficult intubation. 4)Allergy to study medication. 5)Anticipated major blood loss. 6)Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the primary outcome is to arrive at the best time interval before induction, of dexmedetomidine infusion at which adequate blunting of hemodynamic stress response to intubation is achieve.Timepoint: immediately after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Measurement of hemodynamic response during surgery. 2) Complications related to drugs and airway management procedure. 3) Number of attempts to achieve successful intubation.Timepoint: One minute, three minutes, five minutes, fifteen minutes and every half an hour intraoperatively. | — |
Countries
India
Contacts
Public ContactREENA
INSTITUTE OF MEDICAL SCIENCES,
Outcome results
None listed