Comparing the Effects of Amnion Chorion Membrane and Collagen Membrane with Bone Graft in Treating Tooth Bone Defects: A Clinical Study

A Comparative evaluation of the efficacy of amnion chorion membrane and collagen membrane with demineralized bone graft in intrabony defects-a split mouth randomized clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076355

Enrollment

Registered

2024-11-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Amnion chorion membrane: 12 sites will be selected based on inclusion criteria and after open flap debridement Amnion chorion membrane will be placed along with bone graft and flap will

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 32 to 49 years in both genders Systemically healthy patients Diagnosed with generalized chronic periodontitis Evidence of intrabony defects Pocket depth greater than 5mm

Exclusion criteria

Exclusion criteria: Pregnant or lactating women Patients taking any medication 3 months prior to the study Receiving any periodontal treatment 6 months prior to study initiation. Former or Current smokers.

Design outcomes

Primary

Measure	Time frame
Plaque index, Gingival Index, Periodontal Pocket Depth, Clinical Attachment Level.Timepoint: baseline,3months and 6months	—

Secondary

Measure	Time frame
Bone fillTimepoint: baseline and 6months	—

Countries

India

Contacts

Public ContactDr. Pendyala Neelima

GSL Dental College and Hospital

anu3267@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026