Health Condition 1: K929- Disease of digestive system, unspecified
Conditions
Interventions
Intervention1: 1:1 ratio of Ketamine-Propofol Admixture: Effect of 1:1 ratio of Ketamine-Propofol Admixture on Blood pressure for 20 minutes post induction of anaesthesia.
Control Intervention1: 1:3 R
Sponsors
MS Ramaiah Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with American Society of Anaesthesiologists (ASA) Grading I E to III E. 2.Patients scheduled for emergency laparotomy under General Anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of difficult intubation, abnormal airway examination, cardiac morbidities. 2. Patients on angiotensin converting enzyme inhibitors and angiotensin receptor blockers medications 3. Patients with uncontrolled hypertension. 4. Patients with existing hypotension on inotrope support. 5. Patients with allergy of any of the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison between 1:1 and 1:3 ratios of ketamine-propofol admixture with requirement of norepinephrine.Timepoint: First 20 minutes after induction of anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess and compare the incidence and severity of post induction hypotension.Timepoint: First 20 minutes after induction of anaesthesia;To assess and compare the intubation conditions using intubation scoring.Timepoint: First 20 minutes after induction of anaesthesia | — |
Countries
India
Contacts
Public ContactDr Yatish B
MS Ramaiah Medical College
Outcome results
None listed