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Comparing two methods to improve gum thickness around dental implants using blood-derived grafts vs gum grafts

Comparative evaluation of soft tissue parameters and crestal bone changes around implants in sites with thin gingival phenotype using Advanced platelet rich fibrin (A-prf) versus Connective tissue graft (ctg) â?? A randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076319
Enrollment
30
Registered
2024-11-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K084- Partial loss of teeth

Interventions

Intervention1: Implant placement with Advanced platelet rich fibrin(A-PRF)membrane: A total of 30 implants will be placed with the implant surgical guide in systemically healthy patients selected base

Sponsors

Ivaturi Naga Surya Akhila
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Thin gingival phenotype with peri-implant mucosal thickness of 2mm or less and to have 1 missing tooth with the presence of 2 natural adjacent teeth. Edentulous spaces with adequate ridge dimension for implant placement. Absence of periapical pathology adjacent to the edentulous site. Patients who are motivated, highly compliant, with good oral hygiene practice Patient should not have undergone a bone increasing procedure before or during the dental implant. Patient should be free from any periodontal disease.

Exclusion criteria

Exclusion criteria: Patients with any systemic disease and medications that will interfere with treatment outcome. Patients with known risk factors and risk modifiers which can influence the overall outcome of treatment were excluded from the study. Pregnant and lactating women. Persons who are not surgically fit for implant placement. Presence of active periodontal disease.

Design outcomes

Primary

MeasureTime frame
To compare and evaluate the width and thickness of keratinized tissue around implants using A-PRF vs CTG. Timepoint: At baseline ,3 months and 6 months.

Secondary

MeasureTime frame
To compare and evaluate the crestal bone levels using intra-oral periapical radiograph around implants placed using A-PRF vs CTG. Timepoint: At 3 months and 6 months;To compare and evaluate the postoperative pain using visual analogue scale (VAS) in A-PRF group vs CTG group Timepoint: At 1st and 14th day

Countries

India

Contacts

Public ContactDr.Ivaturi Naga Surya Akhila

Gsl Dental College

anu3267@gmail.com9985313267

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026