Patients having heart surgery received a nerve block in their chest with a medicine called ropivacaine, sometimes combined with another medicine called dexmedetomidine, to help manage pain after surgery.

Efficacy of dexmedetomidine as an adjunct to Ropivacaine in pectoral nerve block in cardiac surgery .A prospective randomized double blinded trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076280

Enrollment

Registered

2024-11-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system

Interventions

Intervention1: Pectoralis block with Ropivacaine -Dexmedetomidine: 20ml of drug made with 0.125% ropivacaine and 1mcg/kg dexmedetomidine given before extubation on bilateral side in patients undergoin

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient giving consent 2.Age between 18-60years 3.ASA II & II 4.Patients undergoing elective cardiac surgery.(MVR,ASD)

Exclusion criteria

Exclusion criteria: Patients not giving consent. Patients with history of allergy to study drugs(ropivacaine,dexmedetomidine). Patients having abnormal coagulation profile Pre operative haemodynamic instability.(Congestive heart failure ,uncontrolled AF). Patients with moderate to severe PAH,LVEF less than 40%.

Design outcomes

Primary

Measure	Time frame
1.Pain scores (VAS two hourly) in first 24 hours after extubation . 2.Total fentanyl(0.5mics/kg) consumption in first 24 hours. Timepoint: 1.Pain scores (VAS two hourly) in first 24 hours after extubation . 2.Total fentanyl(0.5mics/kg) consumption in first 24 hours.	—

Secondary

Measure	Time frame
1.Time of first rescue analgesia. 2.Length of icu stay. 3.Duration of mechanical ventilation after surgery. 4.Hemodynamic variables two hourly (MAP and heart rate). 5.Drug related side effects(delirium and sedation). Timepoint: Hemodynamic variables 2hourly (MAP and Heart rate)	—

Countries

India

Contacts

Public ContactDr Nitesh Sinha

Rajendra Institute of Medical Sciences

shiopriye@gmail.com9986743162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026