Health Condition 1: 4- Measurement and Monitoring
Conditions
Interventions
Intervention1: Buccal Oxygenation group: Apneic oxygenation is given through modified Buccal RAE tube from the start of Apnea till intubation
Control Intervention1: Nasal Oxygenation group: Apneic oxy
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Any Adult patients presenting to the Emergency Department with hypoxia requiring rapid sequence intubation
Exclusion criteria
Exclusion criteria: 1. Age less than18 years 2. Pregnant Women 3. Patients who are not properly preoxygenated to the standard RSI protocol of a goal of 3 minutes with 100 percent FiO2. 4. Patients intubated in cardiac or traumatic arrest 5. Hypotension SBP less than 90mmHg 6. Patients intubated without an apneic period-awake intubation 7. The treating emergency physician feels a specific approach to preoxygenation is required between induction, paralysis to successful intubation e.g. a patient in whom provider felt a need to require bag- valve-mask ventilation prior to laryngoscopy, a patient with unstable facial fractures in whom nasal canula cannot be applied
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of hypoxia (SPO2 = 93% or fall in SPO2 = 5%) from start of apnoea (time of NMB agent administration) until 2 minutes after successful intubation.Timepoint: Preoxygenation to 2 minutes after successful intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the PaO2 values at the start of Apnea period and 2 minutes after successful intubation between the two groups.Timepoint: Preoxygenation to 2 minutes after successful intubation;To compare lowest arterial oxygen saturation measured by continuous pulse oximetry (SPO2) between induction and 2 minutes after successful endotracheal tube placement.Timepoint: Preoxygenation to 2 minutes after successful intubation;To compare the incidence of severe hypoxaemia (SPO2 less than 80%) from start of apnoea (time of NMB agent administration) until 2 minutes after successful intubationTimepoint: Preoxygenation to 2 minutes after successful intubation;4) To compare the First pass success rate (proportion of successful intubation on first laryngoscopy attempt)Timepoint: Preoxygenation to 2 minutes after successful intubation | — |
Countries
India
Contacts
Public ContactDr Manu Ayyan
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed