Health Condition 1: K77- Liver disorders in diseases classified elsewhere
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: Nil: Nil
Sponsors
Department of Liver anaesthesia and critical care
Eligibility
Inclusion criteria
Inclusion criteria: All patients aged between 18-65 years who are undergoing living donor liver transplantation at our institution.
Exclusion criteria
Exclusion criteria: Age less than 18 years Patient refusal Diagnosed with infections like Empyema, spontaneous bacterial peritonitis intra-operatively AKI within 7 days prior to transplant, in the preoperative period Patient posted for re-exploration/surgery within POD 2. Patient on CRRT – intra op and post operative
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the change in lactate over 12 hours (delta lactate 0-12) as an early marker for early allograft dysfunction in Living donor liver transplant recipient (LDLTR) in early post-op periodTimepoint: 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the change in lactate over 6 hours (delta lactate 0-6) and 24 hours (delta lactate 0-24) as markers for early allograft dysfunction in LDLTR in the early postoperative period. To examine the association between delta lactate levels and postoperative incidence of sepsis, AKI, prolonged mechanical ventilation, and biliary complications. To examine the association between delta lactate levels and length of hospital stay, ICU stay, and 30-day and 90-day mortality ratesTimepoint: from POD - 0 to discharge from hospital, with 30 day and 90 day mortality | — |
Countries
India
Contacts
Public ContactElavarasan
Dr Rela institute and medical center
Outcome results
None listed