Comparing how often breathing issues occur during and after surgery when using two drugs, sugammadex and neostigmine, after sinus surgery

To compare the frequency of perioperative respiratory adverse events using sugammadex versus neostigmine following functional endoscopic sinus surgery - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076218

Enrollment

Registered

2024-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Reversal agent: Sugammadex 4mg/kg intravenous, At the time of extubation Control Intervention1: Reversal agent: Neostigmine 0.05mg/kg + Glycopyrrolate 0.4mg intravenous at the time of E

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status I and II 2.Patients undergoing functional endoscopic sinus surgery

Exclusion criteria

Exclusion criteria: 1.Known hypersensitivity to study drugs 2. History of any Respiratory disorder or Respiratory Tract Infection 3. History of drug abuse or Smoking 4. Serum creatinine more than 1.5 mg per dl

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study is to assess the frequency of Perioperative respiratory adverse events following Functional Endoscopic Sinus Surgery. Timepoint: at the time of extubation	—

Secondary

Measure	Time frame
1. Time to recovery of neuromuscular function 2. Hemodynamic Variation 3. Post-operative complications, if any.Timepoint: after extubation till 30 min	—

Countries

India

Contacts

Public ContactMandeep Saini

Sri Guru Ram Das Institute of Medical Sciences and Research

drgaganjot@yahoo.com8198014504

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026