Health Condition 1: L814- Other melanin hyperpigmentation
Conditions
Interventions
Intervention1: cysteamine 5% cream: Cysteamine, an aminothiol derived from the breakdown of coenzyme A, is synthesized in various cell types. It demonstrates antioxidant properties and plays a role in
Sponsors
government medical college and hospital chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Patients of 18-50 years of age with clinical diagnosis of facial melasma.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating mothers. 2.Patients with any severe systemic illness requiring systemic treatment of more than 4 weeks. 3.Patients received any oral treatment or any procedural treatment for melasma in the preceding four weeks. 4.Patients with personal or familial history of depigmenting disorders like vitiligo.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Reduction in melasma severity assessed using the modified Melasma Area and Severity Index (mMASI) score. 2.Reduction in pigmentary lesions assessed through clinical photography and dermoscopic evaluation. Timepoint: from baseline to 13 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Patient-reported outcomes: Evaluation of treatment satisfaction and improvement in melasma. 2. Adverse effects: Monitoring and categorization of adverse events related to each treatment using the Numerical Rating Scale (NRS). Timepoint: from baseline to 13 weeks | — |
Countries
India
Contacts
Public ContactDr Oshin Madaan
GOVERNMENT MEDICAL COLLEGE AND HOSPITALCHANDIGARH
Outcome results
None listed