This is a study which will compare the reduction of occurrence of seizures during febrile episodes in children between 6 to 60 months using two drugs in two different groups( Levetiracetam Vs Clobazam) which are routinely used to control seizures and will help us find the better drug for treatment.

A Randomized Controlled Trial Comparing the Prevention of Febrile Seizures in Children with Intermittent Oral Levetiracetam for Two weeks Versus Clobazam - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076213

Enrollment

Registered

2024-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G408- Other epilepsy and recurrent seizures

Interventions

Intervention1: Levetiracetam: it is a drug use to treat seizures which will be given for a period of six months intermittently for 14 days only during febrile period by oral route starting on day 1 of

Eligibility

Inclusion criteria

Inclusion criteria: All the children coming in paediatric OPD and emergency who are newly diagnosed with febrile seizures

Exclusion criteria

Exclusion criteria: 1.Intracranial infections and past episodes of seizure without fever 2. Brain injury/intracranial bleed 3. Currently taking medications to treat epilepsy 4. Children whose parents will not consent for the study

Design outcomes

Primary

Measure	Time frame
To compare the effectiveness of Levetiracetam Vs Clobazam in preventing the recurrence of febrile seizureTimepoint: The Outcome will be assessed at the end of 6months after start of enrollment.	—

Secondary

Measure	Time frame
To compare the adverse effects of using Levetiracetam Vs Clobazam among such patientsTimepoint: The Outcome will be assessed at the end of 6months after start of enrollment.	—

Countries

India

Contacts

Public ContactDr Pancham Kumar

Indira Gandhi Medical College and Hospital, Shimla

shrutimadhur05@gmail.com7726824351

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026