To know the postoperative analgesic effect of oral pregablin and oral clonidine in lower limb surgeries in spinal anaesthesia

To Compare Postoperative Analgesic Effect of Oral Pregabalin versus Oral Clonidine in Lower Limb Surgeries Under Spinal Anaesthesia - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076206

Enrollment

Registered

2024-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal Anaesthesia: All the patients will received 3ml 0.5% hyperbaric bupivacaine intrathecally Control Intervention1: Analgesic effect of drugs: Each group will be given the study dru

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of anesthesiologist class I, class II patients aged 18-65 years of either sex. 2. Patients posted for lower limb surgeries under spinal anesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with hypersensitivity to study drugs 2. Patients suffering from central nervous system disorder and coagulation disorders 3. Contraindications to regional anesthesia such as anatomic disorders of spine, shock, local site infections, peripheral neuropathy 4. Opioid dependents 5. Patient suffering from chronic pain conditions

Design outcomes

Primary

Measure	Time frame
Effectiveness of oral pregabalin, oral clonidine and placebo on postoperative analgesia in lower limb surgeries under spinal anesthesia.Timepoint: from the end of surgery till 24 hours	—

Secondary

Measure	Time frame
Requirement of rescue analgesics in 24hrs post operatively among all the three groups and Hemodynamic changes. Timepoint: from the end of surgery till 24 hours	—

Countries

India

Contacts

Public ContactNavdeep Kumar

Sri Guru Ram Das Institute of Medical Sciences and Research

pooja.monga259@gmail.com8968088773

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026