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Comparing pigmentation response in patients of Vitiligo post intervention by creating micro trauma to the affected skin followed by application of 5-Fluorouracil cream or Tacrolimus cream

Comparing efficacy of microneedling with topical 5-Fluorouracil Vs microneedling with topical Tacrolimus in Vitiligo: an interventional study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076203
Enrollment
70
Registered
2024-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: microneedling with topical 5 % Fluorouracil cream: microneedling creates minute pores into dermis of skin and 5% Fluorouracil cream is a thymidylate synthetase inhibitor required during

Sponsors

Commandant, Base hospital delhi cantt
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of stable vitiligo visiting department of dermatology, Base hospital Delhi cantt.

Exclusion criteria

Exclusion criteria: Pregnant women. Age below 6 years and above 70 years. Lesions over perioral, periocular, patches on the mucosal membrane. Positive Koebner phenomenon. Patients with other autoimmune comorbidities. Patients with coagulation diseases or receiving anticoagulants. Chronic viral infections of HIV, HBV, HCV. High risk of keloid or hypersensitivity to the studied drug

Design outcomes

Primary

MeasureTime frame
To compare the intensity of re – pigmentation following intervention. Timepoint: every month till 3 months & follow up further 3 months—

Secondary

MeasureTime frame
To measure the rate of re – pigmentation in previously depigmented skin lesions.Timepoint: every month till 3 months & follow up further 3 months—

Countries

India

Contacts

Public ContactAvinash Sai

Base Hospital Delhi Cantonment

shail951504@gmail.com7023777714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026