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Observing the human amniotic membrane which act as a regenerative material in necrotic mature teeth. for Reduction of infection size and regain of pulp response will be assessed at a time period of 3, 6, 9 and 12 months.

Assessment of human amniotic membrane as an extracellular matrix scaffold for guided endodontic repair in necrotic mature permanent teeth- A clinical study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/11/076142
Enrollment
25
Registered
2024-11-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Human amniotic membrane: Used as a scaffold Intervention2: NIL: NIL

Sponsors

Dr Supriya Kumari
Lead Sponsor
Supriya Kumari
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients between 18–40 years of age with no sex predilection. 2) Non-contributory medical history. 3) Maxillary anterior with single root and single canal with closed root apex. 4) Necrotic pulp nonresponsive to thermal tests, with or without periapical radiolucency (Periapical index score 0-2).

Exclusion criteria

Exclusion criteria: 1) Teeth with immature roots. 2) Non restorable teeth 3) Positive response to cold testing, presence of sinus tract or swelling. 4) Pregnant and lactating mothers

Design outcomes

Primary

MeasureTime frame
Reduction of periapical radiolucency visually using intraoral periapical radiograph.Timepoint: 1 year—

Secondary

MeasureTime frame
Regain in pulp sensibilityTimepoint: 1 year—

Countries

India

Contacts

Public ContactDr Rashmi NC

Bapuji Educational Association(BEA)

ncrashmi@yahoo.in7347228077

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026