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Efficacy Of Addition Of Clonidine In Transversus Abdominis Plane(TAP) Block

Randomized Double Blind Case Control Study To Evaluate The Efficacy Of Addition Of Clonidine In Transversus Abdominis Plane(TAP) Block - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076118
Enrollment
80
Registered
2024-11-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Injection Clonidine Along with 0.25% Bupivacaine in B/L Subcoastal Approach: Injection Clonidine 75mcg vs Normal Saline along with 20ml 0.25% Bupivacaine in Bilateral Sub Coastal TAP B

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing Laparoscopic Cholecystectomy under ASA grade I&II Including both genders between the ages 18-80yrs Normal coagulation profile

Exclusion criteria

Exclusion criteria: Patient refused to give informed consent. Coagulation disorders Allergic to Local Anaesthetic History of cardiac, respiratory, renal, or hepatic failure Pregnant women History of previous laparotomy and abdominal surgeries Local site infection Patients with underlying comorbidities (ASA III/IV) Patients with significant peripheral neuropathy Patients with coagulopathy and bleeding disorders Patients with previous history of drug abuse

Design outcomes

Primary

MeasureTime frame
To evaluate the degree of postoperative analgesia with Transversus Abdominis Plane block (Sub Coastal Approach) with 20ml 0.25% Bupivacaine and with 20ml 0.25% Bupivacaine and clonidine 150Mcg in patients undergoing lap cholecystectomyTimepoint: POST OPERATIVE PERIOD AFTER 1 HOIUR AFTER 2 HOURS AFTER 4 HOURS AFTER 8 HOURS AFTER 12 HOURS AFTER 24 HOURS

Secondary

MeasureTime frame
Effect of clonidine on hemodynamic both intra-operatively and post-operatively To determine the additional use of opioids in postoperative analgesia To predict the incidence of Post Operative Nausea and Vomiting (PONV) and any local complications Timepoint: POST OPERATIVE PERIOD AFTER 1 HOUR AFTER 4 HOURS AFTER 8 HOURS AFTER 12 HOURS AFTER 24 HOURS

Countries

India

Contacts

Public ContactDr SPS Bedi

Indus International Hospital

spsbedi@indushealthcare.in9814210650

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026