A clinical trial to compare the effect of Antibody toothpaste, Anticaries toothpaste and regular toothpaste against bacteria in saliva

Comparative evaluation of Antibacterial efficacy of Immunoglobulin Y (IgY) toothpaste, Fluoridated toothpaste and non-Fluoridated toothpaste on salivary Streptococcus mutans - A double-blind, Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076114

Enrollment

Registered

2024-11-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Immunoglobulin Y (IgY) toothpaste: Toothpaste form 0.25 grams of toothpaste to be used twice daily for 45 days Control Intervention1: Fluoridated toothpaste: Toothpaste form 0.25 grams

Eligibility

Inclusion criteria

Inclusion criteria: 12 to 15 years of age Both male and female are included Caries active individuals (Caries active individuals are those who have at least one carious tooth surface) Subjects who are willing to follow the instructions given during the course of study

Exclusion criteria

Exclusion criteria: Subjects who have received antibiotics 2 weeks prior to the study. Subjects using other oral hygiene aids like Mouthwash, dental floss, water floss. Subjects with systemic illness. Subjects with history of allergy to egg.

Design outcomes

Primary

Measure	Time frame
Bacterial count of Streptococcus mutansTimepoint: 45 days after using respective toothpaste	—

Secondary

Measure	Time frame
Decrease in colony count of bacteria Streptococcus mutansTimepoint: 15th day after using respective toothpaste 30th day after using respective toothpaste	—

Countries

India

Contacts

Public ContactDr R Palanivel Pandian

Best Dental Science College

doctor.subhashini@gmail.com9629975348

Outcome results