Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intranasal Dexmedetomidine 2 mcg/kg via atomiser: Alpha 2 agonist, intranasal Dexmedetomidine 2 mcg/kg 30 minutes prior induction via atomiser.
Control Intervention1: intransal magnesiu
Sponsors
Smt Bhikiben Kanjibhai Shah Medical Institute and Research Center
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to sign written and informed consent. Male or Female patients between 18 to 65 years of age. Patients belonging to American Society of Anaesthesiologists(ASA) physical status I and II. Patients posted for elective surgeries under general anesthesia.
Exclusion criteria
Exclusion criteria: Patients unwilling to participate in study. Patients with Body Mass Index greater than 30 Kg per m square. Patients having arrythmias. Patient having heart rate less than 70 beats per minute. Psychiatric patients. Pregnancy and lactating women. Patients belonging to the American Society of Anaesthesiologists (ASA) III and above. Patients allergic to the study drugs. Serum magnesium level greater than 2.5mEq per l.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare intranasal Dexmedetomidine versus magnesium sulphate as atomiser in attenuating heart rate and blood pressure during laryngoscopy under general anesthesiaTimepoint: Haemodynamic responses will be observed at baseline, after test drug administratiion, during induction, during laryngoscopy and intubation and after intubation at 1,3,5,7 and 10 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare intranasal Dexmedetomidine versus Magnesium sulphate as atomiser for observing post operative sedation and side effects.Timepoint: Post operatively sedation status will be assessed half hourly by RAMSAY Sedation Score (RSS) till a score of 2 is achieved | — |
Countries
India
Contacts
Public ContactDr Tejash Sharma
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Outcome results
None listed