A RCT comparing triclosan coated suture with non coated suture in closing midline laparotomies to assess decrease in SSI and Wound dehiscence

Effectiveness of triclosan coated polydioxanone suture in comparison to non coated polydioxanone suture in closure of midline laparotomies in terms of SSI and wound dehiscence a randomized trial. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076107

Enrollment

154

Registered

2024-11-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Triclosan coated polydioxanone suture: dose: MP 2360 microgram/meter Route of administration : Topical Frequency - Single Control Intervention1: Non coated Polydioxanone suture: This

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing midline laparotomy. Both elective and emergency cases. Those who will be treated at RIMS Ranchi between [study duration]

Exclusion criteria

Exclusion criteria: Patients who are planned for second look surgery Patients who are immunocompromised or on immunosuppresants . Patients undergoing stoma reversal surgery.

Design outcomes

Primary

Measure	Time frame
Incidence of Surgical site infection and wound dehiscenceTimepoint: 15 days	—

Secondary

Measure	Time frame
risk ratio of SSI in patients with midline laparotomies.Timepoint: 15 days;To estimate the risk ratio of wound dehiscence in patients with midline laparotomies.Timepoint: 15 days;To estimate the baseline characteristics of patients with midline laparotomies.Timepoint: 15 days	—

Countries

India

Contacts

Public ContactDR PRAGYA SINHA

Rajendra institute of medical sciences

drnmpekka@gmail.com9431358260

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026