Health Condition 1: E649- Sequelae of unspecified nutritional deficiency
Conditions
Interventions
Intervention1: Mothers own milk/ colostrum: Route- Oropharyngeal
Dose- 0.2 ml ofMothers own milk/ colostrum
Duration: Till 32 weeks
Frequency: Every 2 hours for 48 hours, then every 3 hours
Control In
Sponsors
Datta Meghe Institute of Higher Education and Research,
Eligibility
Inclusion criteria
Inclusion criteria: Sick babies with less than 32 weeks of gestation requiring CPAP or ventilation who is not receiving feed directly. 2) Mother plans to pump and provide milk for babies admitted in NICU. 3) NICU admissions less than 24 hrs. of life and inborn babies 4) Ability to begins protocol within 96 hours of life.
Exclusion criteria
Exclusion criteria: Babies having 1. birth asphyxia (cord ph/arterial ph less than7) 2. Presence of significant congenital anomalies 4. Parents not giving consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The serum IgA level values in two groups The incidence of Ventilatory associated pneumoniaTimepoint: Oral application of milk - 24 hours Serum IgA blood values at 7 days of life Septic Screening at 7-10 days Discharge or death at the time of discharge 4-6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Total days of hospital stay The incidence of septicaemia and necrotising enterocolitis Outcome in form of death or dischargeTimepoint: Subject enrolment at 24 hours of life Application of milk at 48 hours of life Estimation of serum IgA level at 7 and 14 days of life Recording of occurrence of septicaemia and necrotising enterocolitis at any of time Collection of Mortality data throughout and at the time of discharge | — |
Countries
India
Contacts
Public ContactDr Amar Taksande
Datta Meghe Institute of Higher Education and Research,Sawangi Meghe.
Outcome results
None listed