Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
Intervention1: Application of 5 fraction schedule of adjuvant radiotherapy in breast cancer patients post breast conservation surgery or mastectomy and evaluation the dosimetric feasibility of the pla
Sponsors
Dr Ananya Nandi
Eligibility
Inclusion criteria
Inclusion criteria: All the following criteria must be met: 1. Age more than 18years 2. Female or male 3. Pathologically proven invasive carcinoma of breast 4. Mastectomy or breast conservation surgery 5. Axillary staging and or dissection 6. Complete microscopic excision of primary tumour 7. Early or locally advanced breast cancer 8. Written informed consent 9. Able to comply with follow up N.B. concurrent Trastuzumab or/and endocrine therapies are allowed.
Exclusion criteria
Exclusion criteria: The patient is ineligible if any of the following exclusion criteria is met: 1. age more than 65 year with pT1G1or 2, ER positive, Her 2 negative pN0M0 invasive disease. 2. Ipsilateral micro-invasive disease and non-gradable tumour. 3. Past history of malignancy 4. Contralateral and or previous ipsilateral breast cancer, including DCIS, irrespective of date of diagnosis. 5. Previous thoracic radiotherapy 6. Distant metastasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the dosimetric feasibility of hypofractionated radiotherapy to Target volumes and Organs at riskTimepoint: During execution of radiotherapy treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Acute adverse effects at 1 month. 2. Chronic adverse events at 6 months. 3. Ipsilateral locoregional tumor control at 6 months. 4. Quality of life before and after completion of radiotherapy and after 6 months.Timepoint: at 6 months | — |
Countries
India
Contacts
Public ContactDr Ananya Nandi
Assistant Professor
Outcome results
None listed