FindTrial
Sign In

To study the effect of supplementation of oral amino acids on the release of Cholecystokinin (CCK) and gallbladder ejection fraction (GBEF) in comparison to standardized meal (4 bread, 20 gm amul butter, 200 ml water): A double blinded randomize d cross over RCT

Effect of gastroduodenal inflammation, permeability, endocrine signaling and microbiome on the pathogenesis of gallbladder dysfunction - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075903
Enrollment
30
Registered
2024-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Oral amino acids sachet: Isoleucine (1250 mg) leucine (2500 mg) lysine (1750 mg) methionine (250 mg) phenylalanine (600 mg) threonine (1150 mg) tryptophan (220 mg) valine (250 mg) Cont

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Informed consent

Exclusion criteria

Exclusion criteria: Refusal to consent Serious life-threatening co-morbidities Institutionalized person GI malignancy NSAID intake Gastrointestinal surgery

Design outcomes

Primary

MeasureTime frame
oral amino acids will elucidate the same amount of gallbladder ejection fraction as compared to standardized meal(4 bread, 20 gm amul butter, 200 ml water)Timepoint: oral amino acids will elucidate the same amount of gallbladder ejection fraction as compared to standardized meal(4 bread, 20 gm amul butter, 200 ml water)—

Secondary

MeasureTime frame
CCK will be secreted in the same amount for both amino acids and fatty meal.Timepoint: CCk levels will be measured at 0 , 15, 30 minutes—

Countries

India

Contacts

Public ContactUsha Dutta

Postgraduate Institute of Medical Education and Research

hhharishhooda21@gmail.com7087627115

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026