To know induction and active phase intervals of labor between PGE2 vaginal pessary and vaginal misoprostol.

Induction and active phase interval between PGE2 vaginal pessary and vaginal Misoprostol (25ug) in singleton primi-gravidae with premature rupture of membranes at or beyond 37 weeks - A randomised controlled trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075880

Enrollment

128

Registered

2024-10-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Propess: Propess is vaginal pessary contaning 10mg of dinoprostone(PGE2) administered vaginally and kept for 24 hours or till the women goes into labor. Control Intervention1: Vaginal M

Eligibility

Inclusion criteria

Inclusion criteria: 1.participants include pregnant women at or beyond 37 weeks of gestation with singleton fetus, vertex presentation, with PROM 1.more than 18 years of age 2.unscarred uterus 3.Bishop score less than or equal to 4

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To compare the induction and active phase (75%effaced,3 cm dilated)interval between PGE2 vaginal pessary and vaginal misoprostol (25mcg) in singleton primigravida with PROM at or beyond 37 weeks.Timepoint: 24 hours since recruitment	—

Secondary

Measure	Time frame
Maternal & perinatal outcomesTimepoint: 8-10 hours from recruitment 48 hours from recruitment	—

Countries

India

Contacts

Public ContactBotla Pushpalatha

Jawaharlal institute of post graduate medical education and research

jipoghod@gmail.com9486008274

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026