Health Condition 1: C00- Malignant neoplasm of lip Health Condition 2: C01- Malignant neoplasm of base of tongue Health Condition 3: C02- Malignant neoplasm of other and unspecified parts of tongue Health Condition 4: C03- Malignant neoplasm of gum Health Condition 5: C04- Malignant neoplasm of floor of mouth Health Condition 6: C05- Malignant neoplasm of palate Health Condition 7: C06- Malignant neoplasm of other and unspecified parts of mouth Health Condition 8: C07- Malignant neoplasm of paro
Conditions
Interventions
Intervention1: positron emission tomography-computed tomography (PET-CECT) based radiation dose escalation in patients with head and neck cancer undergoing radical treatment: Patients will undergo PET
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1)Histologically confirmed diagnosis of HNSCC 2)Tumour sites - head and neck 3)Age - adults between 18-75 years 4)Performance status - ECOG 1-2 5)No prior head and neck radiation therapy - patients undergoing radical/ definitive RT/RT-CT 6)Patients who have understood and agreed to participate in the study by signing written informed consent including regular follow-up
Exclusion criteria
Exclusion criteria: 1)Tissue biopsy diagnosis other than HNSCC 2)Postoperative patients 3)Prior head and neck irradiation 4)Metastatic disease/ palliative status 5)Severe comorbidities 6)Pregnancy 7)Contraindications to PET-CECT 8)Patients unwilling to participate in study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local ControlTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free SurvivalTimepoint: 1 year;Overall SurvivalTimepoint: 1 year;Treatment-related toxicityTimepoint: 1 year;Quality of lifeTimepoint: 1 year | — |
Countries
India
Contacts
Public ContactAnoushka Taneja
Kasturba Medical College, Manipal
Outcome results
None listed