Study for comparing two different doses of same drug in reducing pain medication requirement after surgery

Comparison of effect of two different doses of oral Pregabalin in reducing postoperative analgesia in patients receiving neuraxial anaesthesia for surgical procedures - A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075846

Enrollment

Registered

2024-10-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pregabalin given preoperatively before patients receive spinal anesthesia blockade: One tablet of T.Pregabalin 150mg given per orally 1 hour preoperatively before patients receive spina

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo elective surgeries under neuraxial anaesthesia 2. ASA I and ASA II patients 3. Patients aged 18-65 years 4. Patients with BMI less than 24.9

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Spinal deformities 3. Raised ICP 4. Infection at site of procedure 5. Coagulation disorders

Design outcomes

Primary

Measure	Time frame
To compare the duration of postoperative analgesia between the 3 groups using Visual Analogue ScaleTimepoint: 1hr, 3hr, 6hr, 12hr, 24hr	—

Secondary

Measure	Time frame
To assess level of sedation using Ramsay Sedation Scale both preoperatively and postoperativelyTimepoint: 1hr, 1.5hr, 2hr, 2.5hr, 3hr, 3.5hr, 4hr, 4.5hr, 5hr, 5.5hr, 6hr;The number of rescue analgesic doses required in the first 24 hoursTimepoint: 1hr, 6hr, 12hr, 24hr	—

Countries

India

Contacts

Public ContactDr K Karthik

SRM Institute of Science and Technology

karthikkrishnamoorthy1981@gmail.com9884360796

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026