Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age between 21-55 yrs. 2 presence of at least 20 permanent teeth. 3 Presence of pocket depth � 5mm. 4 Non-vital tooth (pulp necrosis) 5 Presence of radiolucency at peri-apical area with evidence of bone loss from marginal bone to root apex. 6 Radiolucency without root damage. 7 Adult patient who did not received any active periodontal or endodontic treatment in the teeth undergoing treatment.
Exclusion criteria
Exclusion criteria: 1�Tooth with mobility. 2�Individuals with tobacco use, 4�pregnancy or lactation. 5�Use of NSAIDS and antibiotics within the previous 3 months. 6�Suffering with CVD, renal disease, diabetes and hypertension 7�Syndromes or developmental disorders with periodontal disease 8�Horizontal and vertical fractures. 9�Iatrogenic root perforations. 10�Open apices. 11�Tooth that could not be isolated with rubber dam.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ATP RLU values and microbiological analysis of Porphyromonas gingivalis and Enterococcus faecalis from the rootcanal and periodontal pocketTimepoint: at baseline and 3 months post-operative | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque Index, Probing Depth, and Clinical attachment LevelTimepoint: at baseline and 3 months post-operative | — |
Countries
India
Contacts
sibar institute of dental sciences