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Effect of Photodynamic therapy in Endo-Perio Lesions

Evaluation of Photodynamic therapy using Indocyanine green and Methylene Blue in reducing Enterococcus Faecalis and Porphyromonas Gingivalis in Endo-perio lesions. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075837
Enrollment
40
Registered
2024-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: photodynamic therapy using diode laser: photodynamic therapy using Diode Laser with the application of sensitization dye in Endo-Perio Lesions Control Intervention1: photodynamic therap

Sponsors

SIBAR Institute of dental sciences
Lead Sponsor
department of endodontics
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age between 21-55 yrs. 2 presence of at least 20 permanent teeth. 3 Presence of pocket depth � 5mm. 4 Non-vital tooth (pulp necrosis) 5 Presence of radiolucency at peri-apical area with evidence of bone loss from marginal bone to root apex. 6 Radiolucency without root damage. 7 Adult patient who did not received any active periodontal or endodontic treatment in the teeth undergoing treatment.

Exclusion criteria

Exclusion criteria: 1�Tooth with mobility. 2�Individuals with tobacco use, 4�pregnancy or lactation. 5�Use of NSAIDS and antibiotics within the previous 3 months. 6�Suffering with CVD, renal disease, diabetes and hypertension 7�Syndromes or developmental disorders with periodontal disease 8�Horizontal and vertical fractures. 9�Iatrogenic root perforations. 10�Open apices. 11�Tooth that could not be isolated with rubber dam.

Design outcomes

Primary

MeasureTime frame
ATP RLU values and microbiological analysis of Porphyromonas gingivalis and Enterococcus faecalis from the rootcanal and periodontal pocketTimepoint: at baseline and 3 months post-operative

Secondary

MeasureTime frame
Plaque Index, Probing Depth, and Clinical attachment LevelTimepoint: at baseline and 3 months post-operative

Countries

India

Contacts

Public ContactKaturi Kishore Kumar

sibar institute of dental sciences

kishoreuga@yahoo.co.in09000534590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026