Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Hyperbaric Levobupivacaine and Clonidine: 0.5% Hyperbaric Levobupivacaine 3ml with Clonidine 30 µg as single injection , intrathecal administration with total duration 6 hours
Control I
Sponsors
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient willing to sign informed consent. 2. ASA I & ASA II patients undergoing spinal anaesthesia posted for Femur Fracture Surgeries. 3. Age between 18- 65 years. 4.No known history of allergy, sensitivity or other form of reaction to local anesthetics of the ester and amide type.
Exclusion criteria
Exclusion criteria: 1. Patient refusal. 2. Allergy to any drugs including test drug. 3. History of seizure disorder. 4. Patient taking clonidine or any other antihypertensives. 5. Patients with neurological disorders and neuropathies or receiving medications known to influence neuromuscular junction. 6. ASA III, IV, Patients. 7. Any contraindication to Spinal Anaesthesia (local site infection, spine deformity, clotting abnormalities)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to study the sensory and motor blockage characteristics in spinal anaesthesiaTimepoint: motor and sensory blockage characteristics assessed at 0,2,4,6,8,10 minutes then every 5 minutes upto 30 minutes and then every 15 minutes till the end of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| To Assess Sedation Score, Duration of Absolute Analgesia and Effective Analgesia, Number of Rescue Analgesia required in 24 hrs and Complications if any. Timepoint: Four Point Sedation Score will be assessed every 5 minutes for 15 minutes then every 15 minutes till the end of surgery. | — |
Countries
India
Contacts
Public ContactJatin Patel
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Outcome results
None listed