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To understand how the fast the duration of braces treatment will take place with either of two intervention: A platelet rich plasma injection and a low-level laser therapy

Effectiveness of Platelet-rich plasma and Low-level laser therapy in accelerating orthodontic tooth movement :A split mouth-Clinical study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075788
Enrollment
20
Registered
2024-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Platelet rich plasma: platelet rich plasma is freshly prepared from the blood of the participant in the study and administered single dose 0.5 ml in the labial vestibule of oral cavity

Sponsors

Krishna Vishwa Vidhyapeeth School of dental sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having permanent dentition. Patients with Class 1 malocclusion with bimaxillary protrusion, Class II division I malocclusion, mild crowding in the range of 2-4 mm, and were indicated for maxillary first premolar extraction and bilaterally maxillary canine distalization. Age: Patients in the age group of 16-35 years of age.

Exclusion criteria

Exclusion criteria: Patients with poor oral hygiene. Patients with impacted canines. Patients with recent major illness resulting in reduced platelet count. Patients on regular antibiotics, steroids, or anti-inflammatory drugs.

Design outcomes

Primary

MeasureTime frame
Accelerated tooth movementTimepoint: 3 months

Secondary

MeasureTime frame
Pain assessmentTimepoint: 3 months;root resorption of canine toothTimepoint: 3 months

Countries

India

Contacts

Public ContactDr Harshali Zavar

School of Dental Sciences Krishna Institute of Medical Sciences Maharashtra

channapparganiger@gmail.com09986841519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026