Comparison of intranasal versus intravenous dexmedetomidine efficacy to control bleeding in endoscopic sinus surgery

Comparison of intranasal versus intravenous dexmedetomidine efficacy in quality of surgical field visualization in functional endoscopic sinus surgery a prospective randomized controlled clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075785

Enrollment

Registered

2024-10-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: Comparison of intranasal versus intravenous dexmedetomidine efficacy in quality of surgical field visualization in functional endoscopic sinus surgery: a prospective, randomized control

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 to 65 years, BMI 18 to 35kg/m2, American Society of Anaesthesiologists (ASA) physical status I, II.

Exclusion criteria

Exclusion criteria: Patients Refusal for consent, History of any specific drug allergy, BMI more than 35kg/m2, Patients with ischemic and congestive heart disease, arrhythmia, Patients with uncontrolled hypertension, diabetes mellitus, Chronic obstructive pulmonary disease, Hepatic and renal dysfunction,Patients with Juvenile nasopharyngeal angiofibroma, recurrent epistaxis,Patients with a history of nasal allergy or requiring revisional nasal surgery

Design outcomes

Primary

Measure	Time frame
Intranasal administration of dexmedetomidine leads to better quality of surgical field and hemodynamic parameters than intravenous administration of dexmedetomidine in functional endoscopic sinus surgeryTimepoint: total case time is 2hrs patients vital parameters recorded at every 10 min interval till the end of surgery and also visibility of the operative field will be assessed by the surgeon according to the Fromme and Boezaart scale.	—

Measure

Time frame

Intranasal administration of dexmedetomidine leads to better quality of surgical field and hemodynamic parameters than intravenous administration of dexmedetomidine in functional endoscopic sinus surgeryTimepoint: total case time is 2hrs patients vital parameters recorded at every 10 min interval till the end of surgery and also visibility of the operative field will be assessed by the surgeon according to the Fromme and Boezaart scale.

—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactDasari Subha Priyanka

All India Institute of Medical Sciences,Raipur

drmamta12@gmail.com9818113061

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026