Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Tramadol: Tramadol 0.5mg/kg IV to be given 5 minutes before spinal anaesthesia.
Intervention2: Ketamine: Ketamine 0.2 mg/kg IV to be given 5 minutes before spinal anaesthesia.
Intervent
Sponsors
M Thangadurai
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of age 18-45 years. 2. Either sex. 3. ASA physical status I & II undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients having contraindications for spinal anaesthesia like lack of consent, raised intracranial tension, infection at local site, severe aortic stenosis, coagulopathy, cardiovascular instability. 2. Patients with known allergy to study drugs. 3. Patients with BMI > 30 kg/m2. 4. Patients ASA physical status III or more. 5. Patients having major cardiovascular, respiratory, renal, hepatic, metabolic, neurological or endocrine diseases. 6. Patients with failed spinal anaesthesia. 7. Patients requiring general anaesthesia. 8. Patients having history of convulsion. 9. An initial or core temperature more than 37.5 C or less than 35.5 C. 10. Patients receiving intraoperative blood transfusion. 11. Patients receiving any other anti-emetic. 12. Patients receiving tramadol, ketamine or ondansetron in the pre-operative period. 13. Patients having arrhythmia or prolonged QTc. 14. Patients with history of opiod/alcohol /substance abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of shiveringTimepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Severity of intraoperative shivering. 2. incidence of other side effects like nausea, vomiting, sedation.Timepoint: 12 months. | — |
Countries
India
Contacts
Public ContactSudeshna Bhar Kundu
Calcutta National Medical College and Hospital
Outcome results
None listed