comparative study of two group of patients undergoing brain surgeries under general anaesthesia - with a nerve block given just under the skin in the neck and another nerve block in the head vs only nerve block in head in the second group

Effectiveness of ultrasound guided unilateral Superficial cervical plexus block along with scalp block on intraoperative hemodynamic stability and perioperative analgesia in Suboccipital Retro-sigmoid Craniotomy: A Randomized Study - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075726

Enrollment

120

Registered

2024-10-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: USG guided unilateral Superficial cervical plexus block: after induction with General Anaesthesia and administration of Scalp Block, Ultrasound guided superficial cervical plexus block

Eligibility

Inclusion criteria

Inclusion criteria: -patient posted for elective suboccipital retrosigmoid craniotomy -age-18-65 yrs -ASA 1 to 2

Exclusion criteria

Exclusion criteria: 1.patient refusal 2.local infection 3.uncontrolled Hypertension 4.Allergy to experimental drug 5.Patient on beta blocker therapy 6.Body mass index less than 18.5 kg/m2 and more than 35 kg/m2

Design outcomes

Primary

Measure	Time frame
To compare the number of episodes of hemodynamic instability(as a rise in SBP or DBP or MAP by more than 20% during each noxious stimulus either at T1 or T3 or T5 as compared to T0) in suboccipital retrosigmoid craniotomies with unilateral Superficial cervical plexus block along with scalp block VS scalp block alone.Timepoint: Time points for recording are the T0: the time just before the noxious stimuli, T1: 1 minute after the noxious stimuli, T3: 3 minutes after the noxious stimuli, T5: 5 minutes after the noxious stimuli noxious stimuli are pin insertion, skin incision, bone drilling and dura mater incision	—

Measure

Time frame

To compare the number of episodes of hemodynamic instability(as a rise in SBP or DBP or MAP by more than 20% during each noxious stimulus either at T1 or T3 or T5 as compared to T0) in suboccipital retrosigmoid craniotomies with unilateral Superficial cervical plexus block along with scalp block VS scalp block alone.Timepoint: Time points for recording are the T0: the time just before the noxious stimuli, T1: 1 minute after the noxious stimuli, T3: 3 minutes after the noxious stimuli, T5: 5 minutes after the noxious stimuli noxious stimuli are pin insertion, skin incision, bone drilling and dura mater incision

—

Secondary

Measure	Time frame
To compare Heart Rate, Systolic blood pressure/Diastolic Blood pressure and Mean Arterial Blood pressureTimepoint: pin insertion,skin incision,bone drilling and duramater incision,dura closure and skin closure;intraoperative and postoperative cumulative fentanyl consumptionTimepoint: till 24 hours postoperative period;postoperative pain intensity using Critical care Pain Observation Tool after surgeryTimepoint: 4 hours interval upto 24 hours after Surgery;Cervico-cephalic pain using Numeric Pain Rating ScaleTimepoint: at discharge from hospital;Post craniotomy pain using Numeric Pain Rating ScaleTimepoint: at 3 months post surgery	—

Measure

Time frame

To compare Heart Rate, Systolic blood pressure/Diastolic Blood pressure and Mean Arterial Blood pressureTimepoint: pin insertion,skin incision,bone drilling and duramater incision,dura closure and skin closure;intraoperative and postoperative cumulative fentanyl consumptionTimepoint: till 24 hours postoperative period;postoperative pain intensity using Critical care Pain Observation Tool after surgeryTimepoint: 4 hours interval upto 24 hours after Surgery;Cervico-cephalic pain using Numeric Pain Rating ScaleTimepoint: at discharge from hospital;Post craniotomy pain using Numeric Pain Rating ScaleTimepoint: at 3 months post surgery

—

Countries

India

Contacts

Public ContactDr Ipsita Subhadarshini

All India Institute of Medical Sciences, Bhubaneswar

anaes_suma@aiimsbhubaneswar.edu.in7259000696

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026