Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: 6% Hydroxyethyl starch: One group of patient will be receiving 100 ml of 6% Hydroxyethyl starch 30 minutes before Propofol injection
Control Intervention1: Normal saline: One group of p
Sponsors
Dr Chongtham Pushpa Chanu
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients of ASA status I and II 2. Age between 18-65 years old , of either gender 3. Patientd undergoing elective surgery under general anesthesia
Exclusion criteria
Exclusion criteria: 1. Emergency surgeries 2. Known history of allergy to Propofol or 6% Hydroxyethyl starch 3. Hypertensive , diabetes , presence of left ventricular dysfunction, elevated serum creatinine 4. Those in whom hand or forearm veins are not accessible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The preadmininstration of 100 ml of 6% Hydroxyethyl starch 3 to 5 mins before Propofol injection can significantly decrease the incidence of pain on injection with propofol in comparison to normal saline ( 28% VS 53% )Timepoint: The pain on propofol injection will be assessed every 10 seconds before the loss of verbal contact by using a 0-3 Verbal Rating Score | — |
Secondary
| Measure | Time frame |
|---|---|
| There is no significant haemodynamic changes ( Heart rate, SBP, DBP) in both groupsTimepoint: The haemodynamic parameters will be assessed baseline , before induction and 5 mins after intubation. | — |
Countries
India
Contacts
Public ContactDr Satyendra Singh Yadav
Gajra Raja Medical College , Gwalior , Madhya Pradesh
Outcome results
None listed