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Comparing two methods that measure heart function in patients undergoing liver transplantation surgery.

Correlation of Cardiac Output measured by transpulmonary thermodilution versus Pulse Contour analysis in Liver transplant recipients - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075683
Enrollment
50
Registered
2024-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Thermodilution derived cardiac output using a PiCCO catheter at specified times during liver tarnsplant surgery: 15 ml ice cold saline is injected through the central line and cardiac o

Sponsors

Amrita Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients presenting for elective liver transplantation

Exclusion criteria

Exclusion criteria: Emergency transplants Transplants for acute liver failure and acute on chronic liver failure Multiorgan transplants

Design outcomes

Primary

MeasureTime frame
Comparison of cardiac output measured by PiCCO thermodilution versus pulse contour during liver transplant surgeryTimepoint: Specified times during surgery T0 baseline T1 2 h in the dissection phase T2 Anhepatic phase after portal vein shunt T3 10 minutes after reperfusion T4 Skin closure at the completion of surgery

Secondary

MeasureTime frame
Comparison of Global end diastolic volume index versus central venous pressure Extravascular lung water index versus oxygenation indexTimepoint: At specified time points during surgery namely T0 baseline T1 2 h in the dissection phase T2 Anhepatic phase after portal vein shunt T3 10 minutes after reperfusion T4 Skin closure at the end of surgery

Countries

India

Contacts

Public ContactDrKshama Balakrishna

Amrita Institute of Medical Sciences

lakshmi.k.238@gmail.com9496211333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026