Health Condition 1: E086- Diabetes mellitus due to underlying condition with other specified complications
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
Jamia Hamdard
Eligibility
Inclusion criteria
Inclusion criteria: Participants with Diabetes defined as HbA1c less or equal to 6.5% or FPG 126mg/dL or taking anti-diabetic medication.
Exclusion criteria
Exclusion criteria: Individuals with a history of significant alcohol consumption-defined as more than 20 grams of alcohol per day for men and 10 grams per day for women,Individuals with a history of other liver diseases, such as viral hepatitis, autoimmune liver diseases, or liver cirrhosis,Pregnant individuals or those planning to become pregnant during the study period,Participants with severe comorbid conditions that could independently affect glucose metabolism or liver function (e.g., advanced chronic kidney disease, advanced heart failure),Individuals taking medications known to significantly impact glucose metabolism (e.g., corticosteroids) or liver function (e.g., methotrexate),Individuals with TB, any form of malignancies presents or history of HIV- AIDS or any disease that could impair the biomarkers levels,Participants with a history of major psychiatric disorders or cognitive impairment. Individuals currently taking medications that significantly impact glucose metabolism or biomarker levels (e.g., corticosteroids, certain antipsychotics),Individuals with a history of major surgery within the last six months,Individuals with acute infections or inflammatory conditions at the time of recruitment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the serum levels of Biomarkers in all the 4 groups and to correlate them with NAFLD severity assessed by Fibro Scan.Timepoint: Single Time point (Baseline) | — |
Secondary
| Measure | Time frame |
|---|---|
| To apply machine learning techniques to develop & validate predictive models for NAFLD & T2DM based on serum biomarkers & clinical features, & to compare their performance with conventional methodsTimepoint: Single Time point(Baseline) | — |
Countries
India
Contacts
Public ContactDr Vineet Jain
JAMIA HAMDARD
Outcome results
None listed