Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Atracurium: Atracurium is an intermediate-acting, non-depolarizing neuromuscular blocking drug of benzylisoquinolinium class used for endotracheal intubation and provide skeletal muscle
Sponsors
Jawaharlal Nehru Medical College
Eligibility
Inclusion criteria
Inclusion criteria: This research study will include ASA Grades I and II patients between the ages of 18 and 60 who are scheduled for elective surgery and will require general anaesthesia with endotracheal intubation and do not have any concomitant diseases.
Exclusion criteria
Exclusion criteria: 1. Grades III and IV of the ASA 2. Mallampati Grade III and Mallampati Grade IV are both excluded. 3. Expected difficult airway 4. Comorbid systemic problems, including cardiovascular, hepatic, and renal dysfunction, as well as neuromuscular abnormalities. 5. Patients using aminoglycosides, MgSO4 6. Any known allergy to any of the study medications. 7. Women who are pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atracurium is a more effective neuromuscular blocking agent than cisatracurium at the same dose, while higher doses of cisatracurium provide efficient, more rapid onset, with longer duration of action, stable hemodynamic status with no signs of histamine release clinically.Timepoint: At baseline, 0 minute, 1 minute, 3 minutes, 5 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| The onset time, duration of action and haemodynamic parameters will be assessed.Timepoint: 1 minute, 3 minutes, 5 minutes after intubation. | — |
Countries
India
Contacts
Public ContactDr Neeta Verma
Datta Meghe Institute of Medical Science and research
Outcome results
None listed