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Randamized double blind Comparative study comparing efficacy of ondansetron and granisetron for the prophylactic control of postoperative nausea and vomiting in patients undergoing middle ear surgery

Comparison of efficacy of ondansetron and granisetron in prevention of postoperative nausea and vomiting in middle ear surgeries: a prospective randomised double-blind study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075611
Enrollment
50
Registered
2024-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj Ondansetron: 0.1 mg/kg Intravenously before 20mis from extubation Control Intervention1: Inj Granisetron: 0.03 mg/kg Intravenously before 20mis from extubation

Sponsors

Pacific medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1 AND 2

Exclusion criteria

Exclusion criteria: Lack of patient consent patient with a history of drug allergy ASA grade more then 2 history of other gastrointestunal diseases,vomiting or retching within 24 hours before operation history of motion sickness and migraine and psychoactive medication within last 24 hours history of severe/unstable cardiovascular,rspiratory,metabolic,endocrine or neurological disease ,impaired renal and hepatic function

Design outcomes

Primary

MeasureTime frame
Comparative study comparing efficacy of ondansetron and granisetron for the prophylactic control of postoperative nausea and vomiting in patients undergoing middle ear surgeryTimepoint: 6Moths to 1year

Secondary

MeasureTime frame
1.To determine drug related adverse effect. 2.Haemodynamic parameters.Timepoint: 1year

Countries

India

Contacts

Public ContactDR Kishor setti

Pacific medical college and hospital

singhdrrk@yahoo.com9166077724

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026