Checking the difference between various intracanal irrigants like 2% Chlorhexidine, 25% aqueous extract of Propolis and Curcuma Longa extract efficacy.

The comparison of antimicrobial effectiveness of 2% chlorhexidine, 25% aqueous extract of propolis and Curcuma Longa extract as intracanal irrigants: an ex vivo study - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075607

Enrollment

Registered

2024-10-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified Health Condition 2: K040- Pulpitis Health Condition 3: K040- Pulpitis

Interventions

Intervention1: 1. 2% Chlorehexidine 2. 25% aqueous extract of Propolis 3. Curcuma longa extract: 1. 2% chlorehexidine will be used once for each patient with 2 ml syringe during pulpectomy 2. 25% aque

Eligibility

Inclusion criteria

Inclusion criteria: good general health no history of antibiotic coverage radiographic evidence of carious pulp exposure in primary teeth

Exclusion criteria

Exclusion criteria: internal or external root resorption physiological resorption upto one third root length of the selected tooth

Design outcomes

Primary

Measure	Time frame
To see the antimicrobial effect (through culture) of 2% Chlorehexidine , 25% aqueous extract of Propolis and Curcuma longa extract Timepoint: All the samples will be sent for culture immediately after the procedure	—

Secondary

Measure	Time frame
The study will be conducted only at baseline.There will be no follow-up.Timepoint: only baseline;1. Chlorohexidine will have significantly higher antimicrobial effect on microorganisms than 25% aqueous propolis & Curcuma longa extract. 2. 25% aqueous propolis extract will have significantly higher antimicrobial effect on microorganisms than 2% chlorohexidine & Curcuma longa extract. 3. Curcuma longa extract will have significantly higher antimicrobial effect on microorganisms than 2% chlorohexidine & 25% aqueous propolis extract.Timepoint: 1. at baseline 2. at baseline 3. at baseline	—

Measure

Time frame

The study will be conducted only at baseline.There will be no follow-up.Timepoint: only baseline;1. Chlorohexidine will have significantly higher antimicrobial effect on microorganisms than 25% aqueous propolis & Curcuma longa extract. 2. 25% aqueous propolis extract will have significantly higher antimicrobial effect on microorganisms than 2% chlorohexidine & Curcuma longa extract. 3. Curcuma longa extract will have significantly higher antimicrobial effect on microorganisms than 2% chlorohexidine & 25% aqueous propolis extract.Timepoint: 1. at baseline 2. at baseline 3. at baseline

—

Countries

India

Contacts

Public ContactUpasana Sengupta

Maharishi Markandeshwar Deemed to be University

hpsumasogi@gmail.com6206582298

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026