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A study to compare the effects of two different doses of a drug Dexmedetomidine to attenuate stress response to intubation during surgery

Comparison Between Two Different Doses of Intravenous Dexmedetomidine o.5mcg/kg and 1mcg/kg on Hemodynamic Changes During Laryngoscopy and Intubation in Patients Scheduled for Elective Surgeries Requiring General Anesthesia and Intubation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075556
Enrollment
60
Registered
2024-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: atropine: In most of the patients Dexmedetomidine 0.5mcg/kg will maintain hemodynamics but 1mcg/kg in few patients might cause significant bradycardia, if Dexmedetomidine causes bradyca

Sponsors

Dr Somsundar R G
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are willing to give consent patients aged between 18-60 years patients requiring general anesthesia and intubation ASA1 and 2

Exclusion criteria

Exclusion criteria: Patients who ASA 3 AND 4 Patients who are morbidly obese BMI >30 Patients in whom there is anticipated difficult intubation

Design outcomes

Primary

MeasureTime frame
To compare two different doses of dexmedetomidine to attenuate stress response to intubationTimepoint: At baseline, 1min,2min,3min,5min and 10min—

Secondary

MeasureTime frame
to determine the better dose among 0.5mcg/kg and 1mcg/kg of intravenous dexmedetomidine to attenuate stress response to intubationTimepoint: 24hrs—

Countries

India

Contacts

Public ContactDr Chethan Sathya B V

Mandya institute of medical sciences

somurg@gmail.com9686508877

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026