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Comparison between topical and oral minocycline in acne vulgaris

Comparative efficacy and safety of topical and oral minocycline in acne vulgaris - Nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075553
Enrollment
62
Registered
2024-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Topical Minocycline Gel 4%: In Group A Thirty one patients shall receive the topical minocycline gel 4% once daily at bed time for total duration of six weeks. Control Intervention1: Or

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All consecutive patients of acne vulgaris GRADE I AND GRADE II with inflammatory lesions with four weeks of non- treatment. 2. Patients between 18 to 50 years.

Exclusion criteria

Exclusion criteria: 1. Pregnant females breastfeeding females females who are planning to get pregnant. 2. Known hypersensitivity to minocycline. 3. Any severe systemic illness. 4. Patient already on treatment from last four weeks 5. Grade III acne vulgaris

Design outcomes

Primary

MeasureTime frame
1.Reduction in the numbers of inflammatory lesions total number of inflammatory lesions will be counted at baseline and at each visit and reduction in these will be calculated by the formula number of baseline new inflammatory lesions present number of baseline inflammatory lesions 2.Adverse events patients will be administered adverse effects check list to assess for safety. Timepoint: Total duration of treatment 6 weeks follow up will be done every 2 weeks

Secondary

MeasureTime frame
1. Reduction in non-inflammatory lesions 2. Patient self-assessment patients will assess the improvement in acne on a scale of 0 4 Timepoint: Total duration of treatment 6 weeks follow up will be done every 2 weeks

Countries

India

Contacts

Public ContactDr Jasleen Kaur

Govt Medical College and Hospital Chandigarh

jasleenksandhu21@gmail.com8360788396

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026