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A comparison of two methods for giving the drug propofol(drug for inducing anesthesia) in patients undergoing surgery under general anesthesia: one by manual infusion and another target controlled infusion

Comparative Study of Manual Infusion with Target Controlled Infusion for induction with Propofol in Patients Posted for Surgeries Under General Anesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075541
Enrollment
174
Registered
2024-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Delivery of intravenous Propofol: By target controlled infusion Infusion will be based on Schnider pharmacokinetic model by targeting a propofol plasma concentration of 4 mcg/ml And poi

Sponsors

Kodagu Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists physical status grade I and grade II 2. Elective OT cases under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Allergic to the study drug- Propofol 2. History of Asthma and Chronic obstructive pulmonary disease 3. History of any neurological disorder 4. History of Cardiopulmonary disease 5. Pregnant and lactating females 6. Difficult airway or difficult ventilation or difficult laryngoscopy

Design outcomes

Primary

MeasureTime frame
Dose of propofol needed for induction by manual infusion and Target Controlled InfusionTimepoint: Frequency

Secondary

MeasureTime frame
Hemodynamic variability in both the groupsTimepoint: Frequency

Countries

India

Contacts

Public ContactDr Amitha S

Kodagu Institute of Medical Sciences

dramithamahesh@gmail.com7204175765

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026