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Comparative evaluation of Titanium Platelet Rich Fibrin (T-PRF) and collagen membrane in conjunction with synthetic bone graft in the treatment of intrabony periodontal defects: A Clinico radiographic study

Comparative evaluation of Titanium platelet rich fibrin (T-PRF) and xenogenic collagen membrane in conjunction with synthetic bioactive calcium phosphosilicate bone graft in the treatment of intrabony periodontal defects- A clinico radiographic study - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075526
Enrollment
30
Registered
2024-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: T-PRF Membrane: Full thickness mucoperiosteal flap will be raised followed by placement of T-PRF membrane and bioactive calcium phosphosilicate bonegraft(Novabone putty and Novabone Mor

Sponsors

Dr Lekshmi R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with generalised chronic periodontitis. Patients willing to take part in the study. Systemically healthy patients. Presence of 2-3 wall intrabony defects with = 3mm (the distance between the alveolar crest and base of defect) on intraoral periapical radiograph [IOPA] along with interproximal probing depth[PD] = 5mm after phase 1 therapy. Patients with no history of allergy to materials and drugs used or prescribed in this study.

Exclusion criteria

Exclusion criteria: Patients who have undergone periodontal treatment within a period of 1 year. Patients on any medication taken within the last 6 months which may alter the periodontal status. Chronic smokers and alcoholics. Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
To clinically evaluate Probing Pocket depth (PPD),Clinical attachment level (CAL),Thickness of attached gingiva and radiographically (IOPAR or RVG) to evaluate and to measure the intrabony defect (the distance between the alveolar crest and base of defect) Timepoint: at baseline and after 6 months

Secondary

MeasureTime frame
To evaluate clinically and radiographically the regenerative potential of T-PRF and xenogenic collagen membrane in conjunction with bioactive calcium phosphosilicate bonegraft (Novabone putty and Novabone Morsels) in the treatment of periodontal intrabony defects.Timepoint: 6 months

Countries

India

Contacts

Public ContactDR KRISHNA KRIPAL

Rajarajeswari dental college and hospital

kripalkrishna@yahoo.com9632597504

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026