Skip to content

Comparison of the effect of intracanal medicament with local anaesthetic and intracanal medicament with saline on pain after root canal treatment.

Comparison of the effect of calcium hydroxide mixed with bupivacaine hydrochloride and calcium hydroxide mixed with saline on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: A randomized controlled single blind trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075510
Enrollment
60
Registered
2024-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Calcium Hydroxide mixed with Bupivacaine Hydrochloride: 2 scoops of calcium hydroxide powder along with 0.2ml of 0.5% bupivacaine hydrochloride will be used to make a paste and placed i

Sponsors

Dr Shivani Waje
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Mandibular molars with irreversible pulpitis and symptomatic apical periodontitis. Prolonged symptomatic response to cold test Patients with preoperative spontaneous or percussion pain level equal or above 5mm on a visual analogue scale. Teeth with PAI score 1 and 2. The selected tooth should have a contact with an antagonist tooth. Cooperative healthy subjects who are willing to participate in the study and sign the consent form.

Exclusion criteria

Exclusion criteria: Subjects with uncontrolled systemic diseases. History of previous root canal treatment. Presence of swelling or sinus tract with the associated tooth. Presence of periodontal pockets more than 3mm in the associated tooth. Severely damaged teeth. Teeth with root resorption, root fracture or ankylosis. Pregnant patients. Patients having parafunctional habits. Patients taking analgesics and anti-inflammatory drugs during past 3 days. Subjects allergic to local anesthesia. Subjects unwilling to sign the consent form.

Design outcomes

Primary

MeasureTime frame
Postoperative pain scoresTimepoint: Daily for 7 days

Secondary

MeasureTime frame
Intake of rescue medicine for postoperative painTimepoint: 7 days

Countries

India

Contacts

Public ContactDr Shivani Waje

Bharati Vidyapeeth Dental College and Hospital, Navi Mumbai

drrahulrao25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026