Study on clonidine impact on blood flow in patients undergoing upper limb surgery under low interscalene block.

Effect of Clonidine on perfusion index and perfusion index ratio in patients undergoing upper limb surgery undergoing low interscalene block. A double blinded randomized placebo controlled study. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075506

Enrollment

Registered

2024-10-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Clonidine as an adjuvant to bupivacaine .: A portable ultrasound machine (sonosite M-turbo) will be placed over the supraclavicular region and a supraclavicular view of subclavian arter

Eligibility

Inclusion criteria

Inclusion criteria: ASA status 1 or 2 giving consent for upper limb surgery under brachial plexus block by low interscalene approach.

Exclusion criteria

Exclusion criteria: Patients having peripheral vascular disease Patient refusal to the block procedure contraindication to regional anesthesia e.g., any allergy to local anesthetic drugs, block site infection ,coagulation disorders.

Design outcomes

Primary

Measure	Time frame
To compare the PI and PI ratio between the blocked arm with bupivacaine and blocked arm with bupivacaine and clonidine at baseline,5 min,10 min,15 min,20 min and 30 min after placement of the block. To find the cut off value of PI and PI ratio at various time points that can predict the result of brachial plexus block. Timepoint: 5 min,10 min,15 min,20 min,30 min	—

Secondary

Measure	Time frame
To compare the hemodynamic stability(Mean arterial pressure and heart rate)in the two groups.Timepoint: 5 min,10 min,15 min,20 min and 30 min	—

Countries

India

Contacts

Public ContactDr Anuj Jain

AIIMS Bhopal

anuj.jain.mln@gmail.com9755702644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026